Annual report pursuant to Section 13 and 15(d)

Licenses and Exclusive Channel Collaboration Agreements - Additional Information (Detail)

v3.3.1.900
Licenses and Exclusive Channel Collaboration Agreements - Additional Information (Detail)
12 Months Ended
Dec. 31, 2015
USD ($)
Patents
Dec. 31, 2014
USD ($)
UFRF License Agreement [Member]    
Research and Development Arrangement, Contract to Perform for Others [Line Items]    
Minimum annual amount to Texas A&M $ 29,416 $ 32,467
License agreement, original date Jun. 22, 2000  
License agreement, first amendment date Sep. 15, 2000  
License agreement, second amendment date Jul. 10, 2002  
License agreement, third amendment date Sep. 25, 2002  
License agreement, fourth amendment date Mar. 17, 2003  
License agreement, fifth amendment date Apr. 19, 2013  
Patents license expiration period 2017 through 2019  
Termination notice period 90 days  
Company's obligation to pay from percentage of selling price of product 5.00%  
Texas A and M University License [Member]    
Research and Development Arrangement, Contract to Perform for Others [Line Items]    
Minimum annual amount to Texas A&M $ 15,000 $ 0
Number of patent application filed | Patents 2  
Maximum period to cure the breach 60 days  
Termination notice period 90 days  
Company's obligation to pay from percentage of selling price of product 5.00%  
Lantibiotic ECC [Member]    
Research and Development Arrangement, Contract to Perform for Others [Line Items]    
Termination notice period 90 days  
Company's obligation to pay from percentage of selling price of product 25.00%  
Oral Mucositis ECC [Member]    
Research and Development Arrangement, Contract to Perform for Others [Line Items]    
Maximum period to cure the breach 60 days  
Termination notice period 90 days  
Company's obligation to pay from percentage of selling price of product 12.00%