Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

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Commitments and Contingencies - Additional Information (Detail)
6 Months Ended 12 Months Ended
May 10, 2017
USD ($)
Jun. 30, 2017
USD ($)
Milestone
Dec. 31, 2017
USD ($)
Dec. 31, 2013
shares
UFRF License Agreement [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product   5.00%    
Company's obligation to pay from all revenue received from sublicenses   22.00%    
One-time commercialization fee monthly amount for calculation   $ 5,000    
Post-commercialization minimum royalty payments   50,000    
One-time additional royalty payment would be due when total cumulative royalties paid to UFRF exceed amount   $ 2,000,000    
One-time additional payment to UFRF as a percentage of total royalties due to UFRF   10.00%    
Minimum annual maintenance payment on license agreement   $ 10,000    
Quarterly maintenance payment to UFRF under installment plan   $ 2,500    
Termination notice period   90 days    
Texas A and M University License [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product   5.00%    
Post-commercialization minimum royalty payments   $ 100,000    
Initial payment to Texas A&M   5,000    
Minimum consideration for the continuation of the license agreement   $ 15,000    
Number of milestones achieved | Milestone   0    
Texas A and M University License [Member] | Phase 1 Clinical Trial [Member]        
Commitment And Contingencies [Line Items]        
Date of milestone achievement under licensing agreement with Texas A&M   Jun. 01, 2019    
Milestone payment under licensing agreement   $ 50,000    
Texas A and M University License [Member] | Phase 2 Clinical Trial [Member]        
Commitment And Contingencies [Line Items]        
Date of milestone achievement under licensing agreement with Texas A&M   Jun. 01, 2022    
Milestone payment under licensing agreement   $ 100,000    
Texas A and M University License [Member] | Phase 3 Clinical Trial [Member]        
Commitment And Contingencies [Line Items]        
Date of milestone achievement under licensing agreement with Texas A&M   Jun. 01, 2025    
Milestone payment under licensing agreement   $ 150,000    
Texas A and M University License [Member] | Sale Of Licensed Technology [Member]        
Commitment And Contingencies [Line Items]        
Date of milestone achievement under licensing agreement with Texas A&M   Jun. 01, 2026    
Milestone payment under licensing agreement   $ 400,000    
Texas A and M University License [Member] | Minimum [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product   2.00%    
Texas A and M University License [Member] | Scenario, Forecast [Member] | Amendment [Member]        
Commitment And Contingencies [Line Items]        
Minimum consideration for the continuation of the license agreement     $ 25,000  
Lantibiotic ECC [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product   25.00%    
Company's obligation to pay from all revenue received from sublicenses   50.00%    
Number of milestones achieved | Milestone   0    
Number of shares issued | shares       4,392,425
Maximum percentage of primary investment securities to investment of shares issued   10.00%    
Lantibiotic ECC [Member] | Investigational New Drug Application [Member]        
Commitment And Contingencies [Line Items]        
Percentage of number of shares of common stock equal to Base Shares   1.00%    
Lantibiotic ECC [Member] | Phase 2 Clinical Trial [Member]        
Commitment And Contingencies [Line Items]        
Percentage of number of shares of common stock equal to Base Shares   1.50%    
Lantibiotic ECC [Member] | New Drug Application or Biologics License Application [Member]        
Commitment And Contingencies [Line Items]        
Percentage of number of shares of common stock equal to Base Shares   2.50%    
Lantibiotic ECC [Member] | First Regulatory Approval of Oragenics Product [Member]        
Commitment And Contingencies [Line Items]        
Percentage of number of shares of common stock equal to Base Shares   3.00%    
Lantibiotic ECC [Member] | Phase 3 Clinical Trial [Member]        
Commitment And Contingencies [Line Items]        
Percentage of number of shares of common stock equal to Base Shares   2.00%    
Oral Mucositis ECC [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product   12.00%    
Company's obligation to pay from all revenue received from sublicenses   50.00%    
Number of milestones achieved | Milestone   0    
Oral Mucositis ECC [Member] | Phase 2 Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement $ 3,000,000 $ 2,000,000    
Milestone measurement period 24 months 30 days    
Oral Mucositis ECC [Member] | Phase 2b/3 Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 5,000,000    
Milestone measurement period   30 days    
Oral Mucositis ECC [Member] | Regulatory Approval Application Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 5,000,000    
Milestone measurement period   30 days    
Oral Mucositis ECC [Member] | Approval Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 10,000,000    
Milestone measurement period   30 days    
Oral Mucositis ECC [Member] | New Indication Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 5,000,000    
Milestone measurement period   30 days    
Oral Mucositis ECC [Member] | New Product Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 5,000,000    
Milestone measurement period   30 days    
Oral Mucositis ECC [Member] | Maximum [Member]        
Commitment And Contingencies [Line Items]        
Maturity of interest bearing promissory note   12 months