SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

                        Date of Report (Date of Earliest
                         Event Reported): March 26, 2004

                                 ORAGENICS, INC.
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             (Exact name of registrant as specified in its charter)





            Florida                       000-50614               59-3410522
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(State or other jurisdiction of    (Commission File Number)    (IRS Employer
 incorporation or organization)                              Identification No.)
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  12085 Research Drive, Alachua, Florida                           32615
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 (Address of principal executive offices)                      (Zip Code)



                                 (386) 418-4018
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              (Registrant's telephone number, including area code)





         Item 5. Other Events and Regulation FD Disclosure.

         On March 29, 2004 the Company  issued a press release  announcing  that
warrant  holders  exercised 83% of the 1,200,000  outstanding  Series B warrants
prior to their  expiration  on March 24,  2004.  Exercise  of  995,400  Series B
warrants at the $3.00 exercise  price resulted in a total of $2,986,200  million
(U.S.)  received by the Company.  A copy of the press release is filed with this
report as Exhibit 99.1 and incorporated by reference.

Item 7.  Financial Statements and Exhibits.

         (c)      Exhibits

                  99.1     Press Release of the Company dated March 26, 2004.



                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                        ORAGENICS, INC.

                                        By: /s/ Mento A. Soponis
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                                            Mento A. Soponis
                                            President, Principal Executive
                                            Officer and a Member of
                                            the Board of Directors

Dated:  March 29, 2004