| 
               FL 
             | 
            
               | 
            
               001-38122 
             | 
            
               | 
            
               59-3410522 
             | 
          
| 
               (State
                or other jurisdiction 
              of
                incorporation) 
             | 
            
               | 
            
               (Commission
                File Number) 
             | 
            
               | 
            
               (IRS
                Employer 
              Identification
                Number) 
             | 
          
| 
               13700
                Progress Blvd 
             | 
            
               | 
            
               32615 
             | 
          
| 
               (Address
                of principal executive offices) 
             | 
            
               | 
            
               (Zip
                Code) 
             | 
          
| 
               ¨ 
             | 
            
               Written
                communications pursuant to Rule 425 under the Securities Act (17
                CFR
                230.425)  
             | 
          
| 
               ¨ 
             | 
            
               Soliciting
                material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
                240.14a-12)  
             | 
          
| 
               ¨ 
             | 
            
               Pre-commencement
                communications pursuant to Rule 14d-2(b) under the Exchange Act (17
                CFR
                240.14d-2(b))  
             | 
          
| 
               ¨ 
             | 
            
               Pre-commencement
                communications pursuant to Rule 13e-4(c) under the Exchange Act (17
                CFR
                240.13e-4(c))  
             | 
          
| 
               Number 
             | 
            
               Description 
             | 
          |
| 
               99.1 
             | 
            
               Press
                release issue October 31, 2008 as to Alternext US
                notice 
             | 
          
| 
               ORAGENICS,
                INC. 
             | 
          ||
|   | 
              | 
              | 
          
| By: | /s/ David B. Hirsch | |
| 
               David B. Hirsch  | 
          ||
| 
               Chief
                Financial Officer 
             | 
          ||