| 
               FL 
             | 
            
               001-38122 
             | 
            
               59-3410522 
             | 
          ||
| 
               (State
      or other jurisdiction 
              of
      incorporation) 
             | 
            
               (Commission
      File Number) 
             | 
            
               (IRS
      Employer 
              Identification
      Number) 
             | 
          
| 
               13700
      Progress Blvd 
             | 
            
               32615 
             | 
          |
| 
               (Address
      of principal executive offices) 
             | 
            
               (Zip
      Code) 
             | 
          
| 
               ¨ 
             | 
            
               Written
      communications pursuant to Rule 425 under the Securities Act (17 CFR
      230.425) 
             | 
          
| 
               ¨ 
             | 
            
               Soliciting
      material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12) 
             | 
          
| 
               ¨ 
             | 
            
               Pre-commencement
      communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
      240.14d-2(b)) 
             | 
          
| 
               ¨ 
             | 
            
               Pre-commencement
      communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR
      240.13e-4(c)) 
             | 
          
| 
                   Number 
                 | 
                
                   Description 
                 | 
              
| 
                   99.1 
                 | 
                
                   Press
      release issued December 10, 2008 as to Alternext Paris
    notice 
                 | 
              
| ORAGENICS, INC. | |||
| 
                 By:
       
               | 
              /s/ David B. Hirsch | ||
| David B. Hirsch | |||
|       
                 Chief
      Financial Officer 
               | 
              |||