FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  Delfino Dorothy Jean
 2. Date of Event Requiring Statement (Month/Day/Year)
06/01/2007		 3. Issuer Name and Ticker or Trading Symbol
ORAGENICS INC [ONI]
(Last)
(First)
(Middle)
P O BOX 12549		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
CFO AND SECRETARY
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

GAINESVILLE, FL 32604		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy) 05/22/2007(1) 05/23/2011 Common Stock 60,000 $ 0.53 D  
Employee Stock Option (Right to Buy) 09/07/2007(2) 09/08/2011 Common Stock 15,000 $ 0.74 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Delfino Dorothy Jean
P O BOX 12549
GAINESVILLE, FL 32604		       CFO AND SECRETARY  

Signatures

/s/ Dorothy J. Delfino 06/05/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The option is exercisable in three equal annual installments. The first installment became exercisable on May 22, 2007 and the next two installments become exercisable on May 22, 2008 and May 22, 2009.
(2) The option is exercisable in three equal annual installments. The first installment will become exercisable on September 7, 2007 and the next two installments become exercisable on September 7, 2008 and September 7, 2009.The option is exercisable in three equal annual installments. The first installment will become exercisable on September 7, 2007 and the next two installments become exercisable on September 7, 2008 and September 7, 2009.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.