FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
KOSKI FAMILY LP
   2. Issuer Name and Ticker or Trading Symbol
ORAGENICS INC [ORNI] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
1500 WEST UNIVERSITY PARKWAY		 3. Date of Earliest Transaction (Month/Day/Year)
12/28/2009
(Street)

SARASOTA, FL 34243		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/28/2009   J(1)   6,040,000 D $ 0 43,960,000 D (2) (3)  
Common Stock 12/28/2009   J(1)   2,000,000 A $ 0 2,000,000 D (4)  
Common Stock 12/28/2009   J(1)   2,000,000 A $ 0 2,000,000 D (5)  
Common Stock 12/28/2009   J(1)   2,000,000 A $ 0 2,000,000 D (6)  
Common Stock 12/28/2009   J(1)   40,000 A $ 0 40,000 I (7) BY KOSKI MANAGEMENT, INC.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
KOSKI FAMILY LP
1500 WEST UNIVERSITY PARKWAY
SARASOTA, FL 34243		     X    
KOSKI CHRISTINE L
1500 WEST UNIVERSITY PARKWAY
SARASOTA, FL 34243		   X   X    
KOSKI BEVERLY
1500 WEST UNIVERSITY PARKWAY
SARASOTA, FL 34243		     X    
KOSKI ROBERT C
1500 WEST UNIVERSITY PARKWAY
SARASOTA, FL 34243		   X   X    
KOSKI THOMAS L
1500 WEST UNIVERSITY PARKWAY
SARASOTA, FL 34243		     X    

Signatures

 /s/ Edward J. Richardson, as Attorney-in-Fact for CHRISTINE L. KOSKI, BEVERLY KOSKI, KOSKI FAMILY LIMITED PARTNERSHIP, ROBERT C. KOSKI AND THOMAS L. KOSKI   12/30/2009
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Distribution from Koski Family Limited Partnership to its general and limited partners Beverly Koski (through Koski Management, Inc.), Christine L. Koski, Robert C. Koski and Thomas L. Koski.
(2) Shares owned directly by Koski Family Limited Partnership. Shares owned indirectly by Beverly Koski (through Koski Management, Inc.), Christine L. Koski, Robert C. Koski and Thomas L. Koski, each of whom is a general partner of the partnership or the controlling person of a corporate general partner of the partnership.
(3) Each reporting person disclaims beneficial ownership of all indirectly owned securities in excess of such reporting person's pecuniary interest therein, and this report shall not be deemed an admission that the reporting person is the beneficial owner for purposes of Section 16 or any other purpose.
(4) Shares owned directly by Christine L. Koski.
(5) Shares owned directly by Robert C. Koski.
(6) Shares owned directly by Thomas L. Koski.
(7) Shares owned indirectly by Beverly Koski through Koski Management, Inc. of which entity Beverly Koski is the sole shareholder.

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