Exhibit 31.1


I, Robert T. Zahradnik, certify that:


  1. I have reviewed this amended quarterly report on Form 10-QSB of Oragenics, Inc.;


  2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

Date: September 29, 2006


/s/ Robert T. Zahradnik

Robert T. Zahradnik
(Chief Executive Officer)