LOGO

Oragenics, Inc.

4902 Eisenhower Boulevard, Suite

Tampa, Florida 33634

July 11, 2018

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Healthcare and Insurance

100 F Street, N.E.

Washington, D.C. 20549-3628

Attn: Ms. Dorrie Yale

 

  Re: Oragenics, Inc. (the “Company”)

Registration Statement on Form S-1

File No. 333-224950

Request for Acceleration

Dear Ms. Yale:

In accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above referenced Registration Statement on Form S-1 be accelerated so that it will be declared effective at 4:30 p.m., Eastern Time, on Thursday July 12, 2018, or as soon thereafter as is practicable.

Please call Mark Catchur, of Shumaker, Loop & Kendrick, LLP counsel to the Registrant, at (813) 227-2264 with any comments or questions regarding this matter.

 

Very truly yours,

By:

 

/s/ Michael Sullivan

 

Name:  Michael Sullivan

 

Title:    Chief Financial Officer

 

cc: Mark A. Catchur, Shumaker, Loop & Kendrick, LLP