A logo with blue and green letters

Description automatically generated

 

Oragenics, Inc.

1990 Main Street, Suite 750

Sarasota, Florida 34236

 

September 3, 2024

 

VIA EDGAR

 

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549-3628

 

Attn: Jimmy McNamara

 

  Re: Oragenics, Inc. (the “Company”)
    Registration Statement on Form S-1
    File No. 333-281618
    Request for Acceleration

 

Dear Mr. McNamara:

 

In accordance with Rule 461 of Regulation C promulgated under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above referenced Registration Statement on Form S-1 be accelerated so that it will be declared effective at 4:30 p.m., Eastern Time, on September 3, 2024, or as soon thereafter as is practicable.

 

Once the Registration Statement has been declared effective, please confirm that event with our counsel, Mark Catchur, of Shumaker, Loop & Kendrick, LLP, at (813) 227-2264.

 

  Very truly yours,
     
  By: /s/ Janet Huffman
  Name: Janet Huffman
  Title: Chief Financial Officer

 

cc: Mark A. Catchur, Shumaker, Loop & Kendrick, LLP