Exhibit
32.1
CERTIFICATION
PURSUANT TO
18
U.S.C. Section 1350,
AS
ADOPTED PURSUANT TO
SECTION
906 OF THE SARBANES-OXLEY ACT OF 2002
In
connection with the Annual Report of Oragenics, Inc. (the "Company") on Form
10-K for the period ended December 31, 2008 as filed with the Securities and
Exchange Commission on the date here of (the "Report"), I, David B. Hirsch,
Acting Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C.
Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of
2002, that:
(1) The
Report fully complies with the requirements of Section 13(a) or 15(d) of the
Securities Exchange Act of 1934; and
(2) The
information contained in this Report fairly presents, in all material respects,
the financial condition and results of operations of the Company.
A signed
original of this written certification has been provided to the company and will
be retained by the company and furnished to the Securities and Exchange
Commission or its staff upon request.
Dated
this March 31, 2009
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/s/ David B. Hirsch
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David
B. Hirsch
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Acting
Chief Executive Officer
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