Exhibit
23.1
Consent of Independent
Registered Public Accounting Firm
We
consent to the inclusion in this Annual Report (Form 10-K) of Oragenics, Inc. of
our report dated March 31, 2010, with respect to the 2009 financial statements
of Oragenics, Inc. We consent to the incorporation by reference in
the Form S-8 Registration Statements (Nos. 333-110646, 333-150716 and
333-163083) of Oragenics, Inc. pertaining to the Oragenics, Inc. Amended and
Restated 2002 Stock Incentive Plan;
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/s/
Kirkland, Russ, Murphy & Tapp,
PA
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Certified
Public Accountants
Clearwater,
Florida
March 31,
2010