Exhibit 31.1


Certification Pursuant to Securities Exchange Act Rules 13a-14 and 15d-14 as adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002


I, Alan Joslyn, Chief Executive Officer, certify that:


1. I have reviewed this Amendment No. 1 to Annual Report on Form 10-K/A of Oragenics, Inc.; and


2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.



/s/ Alan Joslyn


Alan Joslyn

April 29, 2019

Chief Executive Officer (Principal Executive Officer)