Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

Commitments and Contingencies - Additional Information (Detail)		1 Months Ended		3 Months Ended
	Nov. 30, 2016 USD ($) ft²	Nov. 30, 2017 USD ($)	Oct. 31, 2017	Mar. 31, 2019 USD ($) Milestone
Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Period of lease				5 years
Lease commencement date				Dec. 31, 2014
Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Period of lease	36 months
Lease commencement date				Mar. 01, 2017
Area of Office Space Leased \| ft²	2,207
Expiration period	Feb. 29, 2020
Minimum [Member] \| Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments				$ 9,641
Minimum [Member] \| Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments	$ 4,138
Maximum [Member] \| Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments				$ 10,851
Maximum [Member] \| Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments	$ 4,392
UFRF License Agreement [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from percentage of selling price of product				5.00%
Company's obligation to pay from all revenue received from sublicenses				22.00%
One-time commercialization fee monthly amount for calculation				$ 5,000
Post-commercialization minimum royalty payments				50,000
One-time additional royalty payment would be due when total cumulative royalties paid to UFRF exceed amount				$ 2,000,000
One-time additional payment to UFRF as a percentage of total royalties due to UFRF				10.00%
Minimum annual maintenance payment on license agreement				$ 10,000
Quarterly maintenance payment to UFRF under installment plan				$ 2,500
Patent license expiration month and year				2019-07
Lantibiotic ECC [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from percentage of selling price of product				10.00%
Company's obligation to pay from all revenue received from sublicenses		25.00%		25.00%
Royalty rate based on percentage of net sales		10.00%
Number of milestones achieved \| Milestone				0
Lantibiotic ECC [Member] \| Minimum [Member]
Commitment And Contingencies [Line Items]
Amount required to be expended for advancement of lantibiotic program		$ 1,200,000
Lantibiotic ECC [Member] \| Scenario, Previously Reported [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses			50.00%
Royalty rate based on percentage of product profit			25.00%
Lantibiotic ECC [Member] \| New Drug Application [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement		$ 25,000,000		$ 25,000,000
Milestone measurement period		6 months		6 months
Lantibiotic ECC [Member] \| New Indication Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement				$ 5,000,000
Milestone measurement period				6 months
Lantibiotic ECC [Member] \| New Product Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement				$ 5,000,000
Milestone measurement period				6 months
Oral Mucositis ECC [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from percentage of selling price of product				12.00%
Company's obligation to pay from all revenue received from sublicenses		25.00%		25.00%
Number of milestones achieved \| Milestone				0
Oral Mucositis ECC [Member] \| Maximum [Member]
Commitment And Contingencies [Line Items]
Maturity of interest bearing promissory note				12 months
Oral Mucositis ECC [Member] \| Scenario, Previously Reported [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses			50.00%
Oral Mucositis ECC [Member] \| New Indication Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement				$ 5,000,000
Milestone measurement period				6 months
Oral Mucositis ECC [Member] \| New Product Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement				$ 5,000,000
Milestone measurement period				6 months
Oral Mucositis ECC [Member] \| New Product Application [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement		$ 27,500,000		$ 27,500,000
Milestone measurement period		6 months		6 months