Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

Commitments and Contingencies - Additional Information (Detail)		1 Months Ended			6 Months Ended
	Nov. 30, 2016 USD ($) ft²	Nov. 30, 2017 USD ($)	Oct. 31, 2017	Nov. 30, 2016 USD ($) ft²	Jun. 30, 2019 USD ($) Milestone
Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Period of lease					5 years
Lease commencement date					Dec. 31, 2014
Amendment Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Period of lease					5 years
Lease commencement date					Dec. 31, 2019
Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Period of lease	36 months			36 months
Lease commencement date				Mar. 01, 2017
Area of Office Space Leased \| ft²	2,207			2,207
Expiration period	Feb. 29, 2020
Minimum [Member] \| Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments					$ 9,641
Minimum [Member] \| Amendment Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments					12,870
Minimum [Member] \| Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments	$ 4,138			$ 4,138
Maximum [Member] \| Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments					10,851
Maximum [Member] \| Amendment Alachua Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments					$ 13,338
Maximum [Member] \| Tampa Facility [Member]
Commitment And Contingencies [Line Items]
Monthly lease payments	$ 4,392			$ 4,392
Lantibiotic ECC [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses		25.00%			25.00%
Royalty rate based on percentage of net sales		10.00%
Company's obligation to pay from percentage of selling price of product					10.00%
Number of milestones achieved \| Milestone					0
Lantibiotic ECC [Member] \| Minimum [Member]
Commitment And Contingencies [Line Items]
Amount required to be expended for advancement of lantibiotic program		$ 1,200,000
Lantibiotic ECC [Member] \| Scenario, Previously Reported [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses			50.00%
Royalty rate based on percentage of product profit			25.00%
Lantibiotic ECC [Member] \| New Drug Application [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement		$ 25,000,000			$ 25,000,000
Milestone measurement period		6 months			6 months
Lantibiotic ECC [Member] \| New Indication Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement					$ 5,000,000
Milestone measurement period					6 months
Lantibiotic ECC [Member] \| New Product Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement					$ 5,000,000
Milestone measurement period					6 months
Oral Mucositis ECC [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses		25.00%			25.00%
Company's obligation to pay from percentage of selling price of product					12.00%
Number of milestones achieved \| Milestone					0
Oral Mucositis ECC [Member] \| Maximum [Member]
Commitment And Contingencies [Line Items]
Maturity of interest bearing promissory note					12 months
Oral Mucositis ECC [Member] \| Scenario, Previously Reported [Member]
Commitment And Contingencies [Line Items]
Company's obligation to pay from all revenue received from sublicenses			50.00%
Oral Mucositis ECC [Member] \| New Indication Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement					$ 5,000,000
Milestone measurement period					6 months
Oral Mucositis ECC [Member] \| New Product Milestone Event [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement					$ 5,000,000
Milestone measurement period					6 months
Oral Mucositis ECC [Member] \| New Product Application [Member]
Commitment And Contingencies [Line Items]
Milestone payment under licensing agreement		$ 27,500,000			$ 27,500,000
Milestone measurement period		6 months			6 months