Annual report pursuant to Section 13 and 15(d)


Cover - USD ($)
12 Months Ended
Dec. 31, 2021
Mar. 08, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K/A    
Amendment Flag true    
Amendment Description We are filing this Amendment No. 1 to our Annual Report on Form 10-K for the fiscal year ending December 31, 2021 filed with the Securities and Exchange Commission (the “SEC”) on March 24, 2022 (the “Original Filing”) for the sole purpose of including amended Exhibits 32.1 and 32.2 which contain the Section 906 Certifications of our Principal Executive Officer and Principal Financial Officer due to such Exhibits in the Original Filing containing a typographical error in the date of the applicable fiscal year    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2021    
Current Fiscal Year End Date --12-31    
Entity File Number 001-32188    
Entity Registrant Name ORAGENICS, INC.    
Entity Central Index Key 0001174940    
Entity Tax Identification Number 59-3410522    
Entity Incorporation, State or Country Code FL    
Entity Address, Address Line One 4902 Eisenhower Blvd.    
Entity Address, Address Line Two Suite 125    
Entity Address, City or Town Tampa    
Entity Address, State or Province FL    
Entity Address, Postal Zip Code 33634    
City Area Code 813    
Local Phone Number 286-7900    
Title of 12(b) Security Common Stock $0.001 par value per share    
Trading Symbol OGEN    
Security Exchange Name NYSE    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 80,959,901
Entity Common Stock, Shares Outstanding   116,394,806  
ICFR Auditor Attestation Flag false    
Auditor Firm ID 199    
Auditor Name Mayer Hoffman McCann P.C.    
Auditor Location St. Petersburg, FL