Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

v3.19.1
Commitments and Contingencies - Additional Information (Detail)
1 Months Ended 3 Months Ended
Nov. 30, 2016
USD ($)
ft²
Nov. 30, 2017
USD ($)
Oct. 31, 2017
Mar. 31, 2019
USD ($)
Milestone
Alachua Facility [Member]        
Commitment And Contingencies [Line Items]        
Period of lease       5 years
Lease commencement date       Dec. 31, 2014
Tampa Facility [Member]        
Commitment And Contingencies [Line Items]        
Period of lease 36 months      
Lease commencement date       Mar. 01, 2017
Area of Office Space Leased | ft² 2,207      
Expiration period Feb. 29, 2020      
Minimum [Member] | Alachua Facility [Member]        
Commitment And Contingencies [Line Items]        
Monthly lease payments       $ 9,641
Minimum [Member] | Tampa Facility [Member]        
Commitment And Contingencies [Line Items]        
Monthly lease payments $ 4,138      
Maximum [Member] | Alachua Facility [Member]        
Commitment And Contingencies [Line Items]        
Monthly lease payments       $ 10,851
Maximum [Member] | Tampa Facility [Member]        
Commitment And Contingencies [Line Items]        
Monthly lease payments $ 4,392      
UFRF License Agreement [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product       5.00%
Company's obligation to pay from all revenue received from sublicenses       22.00%
One-time commercialization fee monthly amount for calculation       $ 5,000
Post-commercialization minimum royalty payments       50,000
One-time additional royalty payment would be due when total cumulative royalties paid to UFRF exceed amount       $ 2,000,000
One-time additional payment to UFRF as a percentage of total royalties due to UFRF       10.00%
Minimum annual maintenance payment on license agreement       $ 10,000
Quarterly maintenance payment to UFRF under installment plan       $ 2,500
Patent license expiration month and year       2019-07
Lantibiotic ECC [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product       10.00%
Company's obligation to pay from all revenue received from sublicenses   25.00%   25.00%
Royalty rate based on percentage of net sales   10.00%    
Number of milestones achieved | Milestone       0
Lantibiotic ECC [Member] | Minimum [Member]        
Commitment And Contingencies [Line Items]        
Amount required to be expended for advancement of lantibiotic program   $ 1,200,000    
Lantibiotic ECC [Member] | Scenario, Previously Reported [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from all revenue received from sublicenses     50.00%  
Royalty rate based on percentage of product profit     25.00%  
Lantibiotic ECC [Member] | New Drug Application [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 25,000,000   $ 25,000,000
Milestone measurement period   6 months   6 months
Lantibiotic ECC [Member] | New Indication Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement       $ 5,000,000
Milestone measurement period       6 months
Lantibiotic ECC [Member] | New Product Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement       $ 5,000,000
Milestone measurement period       6 months
Oral Mucositis ECC [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from percentage of selling price of product       12.00%
Company's obligation to pay from all revenue received from sublicenses   25.00%   25.00%
Number of milestones achieved | Milestone       0
Oral Mucositis ECC [Member] | Maximum [Member]        
Commitment And Contingencies [Line Items]        
Maturity of interest bearing promissory note       12 months
Oral Mucositis ECC [Member] | Scenario, Previously Reported [Member]        
Commitment And Contingencies [Line Items]        
Company's obligation to pay from all revenue received from sublicenses     50.00%  
Oral Mucositis ECC [Member] | New Indication Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement       $ 5,000,000
Milestone measurement period       6 months
Oral Mucositis ECC [Member] | New Product Milestone Event [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement       $ 5,000,000
Milestone measurement period       6 months
Oral Mucositis ECC [Member] | New Product Application [Member]        
Commitment And Contingencies [Line Items]        
Milestone payment under licensing agreement   $ 27,500,000   $ 27,500,000
Milestone measurement period   6 months   6 months