Annual report pursuant to Section 13 and 15(d)

Basis of Presentation (Details Narrative)

v3.20.4
Basis of Presentation (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Net loss $ (4,409,083) $ (4,496,560) $ (12,337,296) $ (5,187,760) $ (3,597,278) $ (3,836,549) $ (4,806,460) $ (3,325,717) $ (26,430,699) $ (15,566,003)
Cash used in operations                 (16,952,864) (13,012,843)
Accumulated deficit $ (154,444,983)       $ (127,352,826)       (154,444,983) $ (127,352,826)
Gross proceeds from common stock, preferred stock, warrant exercises, income earned on grants and interest income                 13,000,000  
Series C Preferred Stock [Member]                    
Redemption of shares, net                 5,600,000  
From 2012 through 2020 [Member]                    
Gross proceeds from common stock, preferred stock, warrant exercises, income earned on grants and interest income                 $ 92,000,000